In no way could I describe myself as a cartoonist, the last time I got close to being one was the doodling I did in my school books decades ago. Despite my lack of expertise in the area I have an idea for a cartoon strip which I would post on my blog. The problem is it revolves around real people and the cartoon characters would (to the best of my ability) resemble them.
Could this cause problems? The subjects of this cartoon are a friendly bunch and I wouldn’t want to upset any of them by publishing anything they might take exception to.
Obviously, I am not a lawyer. All this is not legal advice. And other disclaimers.
The very short answer is: it depends but it might be okay.
My understanding is that Satire is always a safe harbour. After all, newspapers print political satire cartoons all the time. To an extent, it depends on if you are saying this is real and/or if you are portraying the person or persons in a negative light.
The other thing about basing characters on real people is that those real people have a hard time identifying themselves.
So my advice would be this – draw the cartoon and then imagine you are the people in question and try to see if you would be offended.